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Combined CCNE1 high‐level amplification and overexpression is associated with unfavourable outcome in tubo‐ovarian high‐grade serous carcinoma

CCNE1 amplification is a recurrent alteration associated with unfavourable outcome in tubo‐ovarian high‐grade serous carcinoma (HGSC). We aimed to investigate whether immunohistochemistry (IHC) can be used to identify CCNE1 amplification status and to validate whether CCNE1 high‐level amplification...

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Detalles Bibliográficos
Autores principales: Chan, Angela MY, Enwere, Emeka, McIntyre, John B, Wilson, Holly, Nwaroh, Chidera, Wiebe, Nicholas, Ou, Young, Liu, Shuhong, Wiedemeyer, Katharina, Rambau, Peter F, Grevers, Xin, Morris, Donald G, Neri, Paola, Gilks, C Blake, Visser, Frank, Le, Nhu, Luo, Li, Cook, Linda S, Köbel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578325/
https://www.ncbi.nlm.nih.gov/pubmed/32391646
http://dx.doi.org/10.1002/cjp2.168