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The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study
Cancer somatic mutations have been identified as a source of antigens that can be targeted by cancer immunotherapy. In this work, expanding on previous studies, we analyze the HLA-presentation properties of mutations that are known to drive resistance to cancer targeted-therapies. We survey a large...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578429/ https://www.ncbi.nlm.nih.gov/pubmed/33133066 http://dx.doi.org/10.3389/fimmu.2020.524968 |