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Knockdown of KCNQ1OT1 attenuates cardiac hypertrophy through modulation of the miR-2054/AKT3 axis

BACKGROUND: Persistent cardiac hypertrophy threatens health worldwide. Long non-coding RNAs (lncRNAs) attracted lots of attention in cardiac diseases such as cardiac hypertrophy. In this study, we aimed to study the function of KCNQ1OT1 in cardiac hypertrophy. METHODS: We first used qRT-PCR to detec...

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Detalles Bibliográficos
Autores principales: Chen, Yiwei, Zhang, Zhifang, Zhu, Diqi, Zhao, Wenchuo, Li, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578479/
https://www.ncbi.nlm.nih.gov/pubmed/33145050
http://dx.doi.org/10.21037/jtd-20-203