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Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels

BACKGROUND AND AIMS: A relationship between treatment outcomes and intestinal microbiota in patients with inflammatory bowel diseases has been demonstrated. Cyclosporine treatment leads to rapid improvement in severe ulcerative colitis. We hypothesized that the potent effects of cyclosporine would b...

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Detalles Bibliográficos
Autores principales: Ota, Shinji, Sakuraba, Hirotake, Hiraga, Hiroto, Yoshida, Shukuko, Satake, Miwa, Akemoto, Yui, Tanaka, Nahoko, Watanabe, Rina, Takato, Maeda, Murai, Yasuhisa, Ueno, Kayo, Niioka, Takenori, Hayakari, Makoto, Ishiguro, Yoh, Fukuda, Shinsaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578528/
https://www.ncbi.nlm.nih.gov/pubmed/33102812
http://dx.doi.org/10.1016/j.bbrep.2020.100811