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Cyclosporine protects from intestinal epithelial injury by modulating butyrate uptake via upregulation of membrane monocarboxylate transporter 1 levels
BACKGROUND AND AIMS: A relationship between treatment outcomes and intestinal microbiota in patients with inflammatory bowel diseases has been demonstrated. Cyclosporine treatment leads to rapid improvement in severe ulcerative colitis. We hypothesized that the potent effects of cyclosporine would b...
Autores principales: | Ota, Shinji, Sakuraba, Hirotake, Hiraga, Hiroto, Yoshida, Shukuko, Satake, Miwa, Akemoto, Yui, Tanaka, Nahoko, Watanabe, Rina, Takato, Maeda, Murai, Yasuhisa, Ueno, Kayo, Niioka, Takenori, Hayakari, Makoto, Ishiguro, Yoh, Fukuda, Shinsaku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578528/ https://www.ncbi.nlm.nih.gov/pubmed/33102812 http://dx.doi.org/10.1016/j.bbrep.2020.100811 |
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