Cargando…

Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats

Recently, the rise of mycotoxin contamination in food materials was found to be due to several factors, including climatic changes’ impact. Therefore, the aim of this study was to provide a novel food product that allows the reduction of aflatoxin impact in animal tissues. Chicory root-extract (CRE)...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdel-Salam, Ahmed M., Badr, Ahmed Noah, Zaghloul, Ahmed H., Farrag, Abdel Razik H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578531/
https://www.ncbi.nlm.nih.gov/pubmed/33102145
http://dx.doi.org/10.1016/j.toxrep.2020.10.012
_version_ 1783598386974294016
author Abdel-Salam, Ahmed M.
Badr, Ahmed Noah
Zaghloul, Ahmed H.
Farrag, Abdel Razik H.
author_facet Abdel-Salam, Ahmed M.
Badr, Ahmed Noah
Zaghloul, Ahmed H.
Farrag, Abdel Razik H.
author_sort Abdel-Salam, Ahmed M.
collection PubMed
description Recently, the rise of mycotoxin contamination in food materials was found to be due to several factors, including climatic changes’ impact. Therefore, the aim of this study was to provide a novel food product that allows the reduction of aflatoxin impact in animal tissues. Chicory root-extract (CRE) was evaluated for its active components, antioxidant potency, and antimicrobial activity. The CRE was utilized to produce functional yogurt (FY) that was evaluated in-vivo using experimental rats. The CRE showed high antioxidant activity and recorded valuable content of the active components. Results also showed a high antimicrobial effect against toxigenic fungal strains. The results have reflected the efficiency of the FY to suppress aflatoxin impacts in the animal tissues and biochemical parameters of rats-serum. An enhancement was recorded inliver and kidney functions for rats taking FY with the presence of aflatoxin. It was concluded that consumption of the FY assisted in suppression of the oxidative stress in rats-tissues.
format Online
Article
Text
id pubmed-7578531
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-75785312020-10-23 Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats Abdel-Salam, Ahmed M. Badr, Ahmed Noah Zaghloul, Ahmed H. Farrag, Abdel Razik H. Toxicol Rep Regular Article Recently, the rise of mycotoxin contamination in food materials was found to be due to several factors, including climatic changes’ impact. Therefore, the aim of this study was to provide a novel food product that allows the reduction of aflatoxin impact in animal tissues. Chicory root-extract (CRE) was evaluated for its active components, antioxidant potency, and antimicrobial activity. The CRE was utilized to produce functional yogurt (FY) that was evaluated in-vivo using experimental rats. The CRE showed high antioxidant activity and recorded valuable content of the active components. Results also showed a high antimicrobial effect against toxigenic fungal strains. The results have reflected the efficiency of the FY to suppress aflatoxin impacts in the animal tissues and biochemical parameters of rats-serum. An enhancement was recorded inliver and kidney functions for rats taking FY with the presence of aflatoxin. It was concluded that consumption of the FY assisted in suppression of the oxidative stress in rats-tissues. Elsevier 2020-10-21 /pmc/articles/PMC7578531/ /pubmed/33102145 http://dx.doi.org/10.1016/j.toxrep.2020.10.012 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Regular Article
Abdel-Salam, Ahmed M.
Badr, Ahmed Noah
Zaghloul, Ahmed H.
Farrag, Abdel Razik H.
Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats
title Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats
title_full Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats
title_fullStr Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats
title_full_unstemmed Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats
title_short Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats
title_sort functional yogurt aims to protect against the aflatoxin b1 toxicity in rats
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578531/
https://www.ncbi.nlm.nih.gov/pubmed/33102145
http://dx.doi.org/10.1016/j.toxrep.2020.10.012
work_keys_str_mv AT abdelsalamahmedm functionalyogurtaimstoprotectagainsttheaflatoxinb1toxicityinrats
AT badrahmednoah functionalyogurtaimstoprotectagainsttheaflatoxinb1toxicityinrats
AT zaghloulahmedh functionalyogurtaimstoprotectagainsttheaflatoxinb1toxicityinrats
AT farragabdelrazikh functionalyogurtaimstoprotectagainsttheaflatoxinb1toxicityinrats