Nrf2: A unifying transcription factor in the pathogenesis of Fuchs’ endothelial corneal dystrophy

Nuclear factor, erythroid 2 like 2 (Nrf2), is an oxidative stress induced transcription factor that regulates cytoprotective gene expression. Thus, Nrf2 is essential for cellular redox homeostasis. Loss or dysregulation of Nrf2 expression has been implicated in the pathogenesis of degenerative disea...

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Detalles Bibliográficos
Autores principales: Lovatt, Matthew, Kocaba, Viridiana, Hui Neo, Dawn Jing, Soh, Yu Qiang, Mehta, Jodhbir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578533/
https://www.ncbi.nlm.nih.gov/pubmed/33099215
http://dx.doi.org/10.1016/j.redox.2020.101763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578533/
https://www.ncbi.nlm.nih.gov/pubmed/33099215
http://dx.doi.org/10.1016/j.redox.2020.101763

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