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Nrf2: A unifying transcription factor in the pathogenesis of Fuchs’ endothelial corneal dystrophy
Nuclear factor, erythroid 2 like 2 (Nrf2), is an oxidative stress induced transcription factor that regulates cytoprotective gene expression. Thus, Nrf2 is essential for cellular redox homeostasis. Loss or dysregulation of Nrf2 expression has been implicated in the pathogenesis of degenerative disea...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578533/ https://www.ncbi.nlm.nih.gov/pubmed/33099215 http://dx.doi.org/10.1016/j.redox.2020.101763 |