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Proliferative Signals in Chronic Lymphocytic Leukemia; What Are We Missing?

Chronic lymphocytic leukemia (CLL) cells cycle between lymphoid tissue sites where they actively proliferate, and the peripheral blood (PB) where they become quiescent. Strong evidence exists for a crucial role of B cell receptor (BCR) triggering, either by (self-)antigen or by receptor auto-engagem...

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Detalles Bibliográficos
Autores principales: Haselager, Marco V., Kater, Arnon P., Eldering, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578574/
https://www.ncbi.nlm.nih.gov/pubmed/33134182
http://dx.doi.org/10.3389/fonc.2020.592205