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Prevention of mitochondrial impairment by inhibition of protein phosphatase 1 activity in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease caused by progressive loss of motor neurons (MNs) and subsequent muscle weakness. These pathological features are associated with numerous cellular changes, including alteration in mitochondrial morphology and function. However...

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Detalles Bibliográficos
Autores principales: Choi, So Yoen, Lee, Ju-Hyun, Chung, Ah-Young, Jo, Youhwa, Shin, Joo-ho, Park, Hae-Chul, Kim, Hyun, Lopez-Gonzalez, Rodrigo, Ryu, Jae Ryun, Sun, Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578657/
https://www.ncbi.nlm.nih.gov/pubmed/33087694
http://dx.doi.org/10.1038/s41419-020-03102-8