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Diminished Sphingolipid Metabolism, a Hallmark of Future Type 2 Diabetes Pathogenesis, Is Linked to Pancreatic β Cell Dysfunction

Gestational diabetes mellitus (GDM) is the top risk factor for future type 2 diabetes (T2D) development. Ethnicity profoundly influences who will transition from GDM to T2D, with high risk observed in Hispanic women. To better understand this risk, a nested 1:1 pair-matched, Hispanic-specific, case-...

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Detalles Bibliográficos
Autores principales: Khan, Saifur R., Manialawy, Yousef, Obersterescu, Andreea, Cox, Brian J., Gunderson, Erica P., Wheeler, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578680/
https://www.ncbi.nlm.nih.gov/pubmed/33103069
http://dx.doi.org/10.1016/j.isci.2020.101566