Cargando…
Diminished Sphingolipid Metabolism, a Hallmark of Future Type 2 Diabetes Pathogenesis, Is Linked to Pancreatic β Cell Dysfunction
Gestational diabetes mellitus (GDM) is the top risk factor for future type 2 diabetes (T2D) development. Ethnicity profoundly influences who will transition from GDM to T2D, with high risk observed in Hispanic women. To better understand this risk, a nested 1:1 pair-matched, Hispanic-specific, case-...
Autores principales: | Khan, Saifur R., Manialawy, Yousef, Obersterescu, Andreea, Cox, Brian J., Gunderson, Erica P., Wheeler, Michael B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578680/ https://www.ncbi.nlm.nih.gov/pubmed/33103069 http://dx.doi.org/10.1016/j.isci.2020.101566 |
Ejemplares similares
-
metGWAS 1.0: an R workflow for network-driven over-representation analysis between independent metabolomic and meta-genome-wide association studies
por: Khan, Saifur R, et al.
Publicado: (2023) -
Pancreatic Cancers with High Grade Tumor Budding Exhibit Hallmarks of Diminished Anti-Tumor Immunity
por: Sadozai, Hassan, et al.
Publicado: (2021) -
The Role of Sphingolipids in the Pathogenesis of Psoriasis
por: Matwiejuk, Mateusz, et al.
Publicado: (2022) -
Roles of ceramide and sphingolipids in pancreatic β-cell function and dysfunction
por: Boslem, Ebru, et al.
Publicado: (2012) -
Roles of Sphingolipid Metabolism in Pancreatic β Cell Dysfunction Induced by Lipotoxicity
por: Véret, Julien, et al.
Publicado: (2014)