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Short-term high-dose gavage of hydroxychloroquine changes gut microbiota but not the intestinal integrity and immunological responses in mice
AIMS: Hydroxychloroquine (HCQ), a widely used antimalarial drug, is proposed to treat coronavirus disease 2019 (COVID-19). However, no report is currently available regarding the direct effects of HCQ on gut microbiota, which is associated with the outcomes of elderly patients with COVID-19. Here, w...
Autores principales: | Pan, Zhi-Yuan, Chang, Yu-Xiao, Han, Ni, Hou, Feng-Yi, Lee, B.J. Yang, Zhi, Fa-Chao, Yang, Rui-Fu, Bi, Yu-Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578705/ https://www.ncbi.nlm.nih.gov/pubmed/33131749 http://dx.doi.org/10.1016/j.lfs.2020.118450 |
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