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Hypoxia-Induced Glioma-Derived Exosomal miRNA-199a-3p Promotes Ischemic Injury of Peritumoral Neurons by Inhibiting the mTOR Pathway

The underlying molecular mechanisms that the hypoxic microenvironment could aggravate neuronal injury are still not clear. In this study, we hypothesized that the exosomes, exosomal miRNAs, and the mTOR signaling pathway might be involved in hypoxic peritumoral neuronal injury in glioma. Multimodal...

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Detalles Bibliográficos
Autores principales: Zhao, Jian-Lan, Tan, Bo, Chen, Gong, Che, Xiao-Ming, Du, Zhuo-Ying, Yuan, Qiang, Yu, Jian, Sun, Yi-Rui, Li, Xiao-Mu, Hu, Jin, Xie, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578720/
https://www.ncbi.nlm.nih.gov/pubmed/33110474
http://dx.doi.org/10.1155/2020/5609637