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Hypoxia-Induced Glioma-Derived Exosomal miRNA-199a-3p Promotes Ischemic Injury of Peritumoral Neurons by Inhibiting the mTOR Pathway
The underlying molecular mechanisms that the hypoxic microenvironment could aggravate neuronal injury are still not clear. In this study, we hypothesized that the exosomes, exosomal miRNAs, and the mTOR signaling pathway might be involved in hypoxic peritumoral neuronal injury in glioma. Multimodal...
Autores principales: | Zhao, Jian-Lan, Tan, Bo, Chen, Gong, Che, Xiao-Ming, Du, Zhuo-Ying, Yuan, Qiang, Yu, Jian, Sun, Yi-Rui, Li, Xiao-Mu, Hu, Jin, Xie, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578720/ https://www.ncbi.nlm.nih.gov/pubmed/33110474 http://dx.doi.org/10.1155/2020/5609637 |
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