CIC Is a Mediator of the ERK1/2-DUSP6 Negative Feedback Loop

DUSP6 functions as an important negative feedback component of the MAPK/ERK signaling pathway. Although DUSP6 expression is tightly regulated by ERK1/2 signaling, the molecular mechanism of this regulation remains partially understood. In this work, we show that the transcriptional repressor CIC fun...

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Detalles Bibliográficos
Autores principales: Ren, Yibo, Ouyang, Zhenlin, Hou, Zhanwu, Yan, Yuwei, Zhi, Zhe, Shi, Mengjin, Du, Mengtao, Liu, Huadong, Wen, Yurong, Shao, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578760/
https://www.ncbi.nlm.nih.gov/pubmed/33103082
http://dx.doi.org/10.1016/j.isci.2020.101635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578760/
https://www.ncbi.nlm.nih.gov/pubmed/33103082
http://dx.doi.org/10.1016/j.isci.2020.101635

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