Newly established gastrointestinal cancer cell lines retain the genomic and immunophenotypic landscape of their parental cancers

Human cancer cell lines are frequently used as model systems to study molecular mechanisms and genetic changes in cancer. However, the model is repeatedly criticized for its lack of proximity to original patient tumors. Therefore, understanding to what extent cell lines cultured under artificial con...

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Detalles Bibliográficos
Autores principales: Hirsch, Daniela, Seyfried, Steffen, Staib, Tobias, Fiedler, David, Sauer, Christian, Ried, Thomas, Witt, Stephanie, Rueckert, Felix, Gaiser, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578805/
https://www.ncbi.nlm.nih.gov/pubmed/33087752
http://dx.doi.org/10.1038/s41598-020-74797-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578805/
https://www.ncbi.nlm.nih.gov/pubmed/33087752
http://dx.doi.org/10.1038/s41598-020-74797-0

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