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Newly established gastrointestinal cancer cell lines retain the genomic and immunophenotypic landscape of their parental cancers
Human cancer cell lines are frequently used as model systems to study molecular mechanisms and genetic changes in cancer. However, the model is repeatedly criticized for its lack of proximity to original patient tumors. Therefore, understanding to what extent cell lines cultured under artificial con...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578805/ https://www.ncbi.nlm.nih.gov/pubmed/33087752 http://dx.doi.org/10.1038/s41598-020-74797-0 |