Quantitative PCR methodology with a volume-based unit for the sophisticated cellular kinetic evaluation of chimeric antigen receptor T cells

Although the cellular kinetics of chimeric antigen receptor T (CAR T) cells are expressed in units of copies/μg gDNA, this notation carries the risk of misrepresentation owing to dramatic changes in blood gDNA levels after lymphocyte-depleting chemotherapy and rapid expansion of CAR T cells. Therefo...

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Detalles Bibliográficos
Autores principales: Yamamoto, Syunsuke, Matsumoto, Shin-ichi, Goto, Akihiko, Ugajin, Miyuki, Nakayama, Miyu, Moriya, Yuu, Hirabayashi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578827/
https://www.ncbi.nlm.nih.gov/pubmed/33087808
http://dx.doi.org/10.1038/s41598-020-74927-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578827/
https://www.ncbi.nlm.nih.gov/pubmed/33087808
http://dx.doi.org/10.1038/s41598-020-74927-8

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