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Proteomic analysis of Drosophila CLOCK complexes identifies rhythmic interactions with SAGA and Tip60 complex component NIPPED-A

Circadian clocks keep time via ~ 24 h transcriptional feedback loops. In Drosophila, CLOCK-CYCLE (CLK-CYC) activators and PERIOD-TIMELESS (PER-TIM) repressors are feedback loop components whose transcriptional status varies over a circadian cycle. Although changes in the state of activators and repr...

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Detalles Bibliográficos
Autores principales: Mahesh, Guruswamy, Rivas, Gustavo B. S., Caster, Courtney, Ost, Evan B., Amunugama, Ravi, Jones, Richard, Allen, David L., Hardin, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578830/
https://www.ncbi.nlm.nih.gov/pubmed/33087840
http://dx.doi.org/10.1038/s41598-020-75009-5