Response of human melanoma cell lines to interferon-beta gene transfer mediated by a modified adenoviral vector

Since melanomas often retain wild type p53, we developed an adenoviral vector, AdRGD-PG, which provides robust transduction and transgene expression in response to p53. Previously, this vector was used for interferon-β gene transfer in mouse models of melanoma, resulting in control of tumor progress...

Descripción completa

Detalles Bibliográficos
Autores principales: David, Taynah I. P., Cerqueira, Otto L. D., Lana, Marlous G., Medrano, Ruan F. V., Hunger, Aline, Strauss, Bryan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578831/
https://www.ncbi.nlm.nih.gov/pubmed/33087767
http://dx.doi.org/10.1038/s41598-020-74826-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578831/
https://www.ncbi.nlm.nih.gov/pubmed/33087767
http://dx.doi.org/10.1038/s41598-020-74826-y

Ejemplares similares