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Response of human melanoma cell lines to interferon-beta gene transfer mediated by a modified adenoviral vector
Since melanomas often retain wild type p53, we developed an adenoviral vector, AdRGD-PG, which provides robust transduction and transgene expression in response to p53. Previously, this vector was used for interferon-β gene transfer in mouse models of melanoma, resulting in control of tumor progress...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578831/ https://www.ncbi.nlm.nih.gov/pubmed/33087767 http://dx.doi.org/10.1038/s41598-020-74826-y |