Prediction of Protein Mutational Free Energy: Benchmark and Sampling Improvements Increase Classification Accuracy

Software to predict the change in protein stability upon point mutation is a valuable tool for a number of biotechnological and scientific problems. To facilitate the development of such software and provide easy access to the available experimental data, the ProTherm database was created. Biases in...

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Detalles Bibliográficos
Autores principales: Frenz, Brandon, Lewis, Steven M., King, Indigo, DiMaio, Frank, Park, Hahnbeom, Song, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579412/
https://www.ncbi.nlm.nih.gov/pubmed/33134287
http://dx.doi.org/10.3389/fbioe.2020.558247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579412/
https://www.ncbi.nlm.nih.gov/pubmed/33134287
http://dx.doi.org/10.3389/fbioe.2020.558247

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