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Prediction of Protein Mutational Free Energy: Benchmark and Sampling Improvements Increase Classification Accuracy
Software to predict the change in protein stability upon point mutation is a valuable tool for a number of biotechnological and scientific problems. To facilitate the development of such software and provide easy access to the available experimental data, the ProTherm database was created. Biases in...
Autores principales: | Frenz, Brandon, Lewis, Steven M., King, Indigo, DiMaio, Frank, Park, Hahnbeom, Song, Yifan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579412/ https://www.ncbi.nlm.nih.gov/pubmed/33134287 http://dx.doi.org/10.3389/fbioe.2020.558247 |
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