α-Cyperone Confers Antidepressant-Like Effects in Mice via Neuroplasticity Enhancement by SIRT3/ROS Mediated NLRP3 Inflammasome Deactivation

α-Cyperone (Cy) is a major active compound of Cyperus rotundus that has various pharmacological activities. But whether Cy possesses antidepressant effect is unknown. In this study, we exposed mice to chronic unpredictable mild stress (CUMS) with or without intervention with Cy. Our results showed t...

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Detalles Bibliográficos
Autores principales: Xia, Baomei, Tong, Yue, Xia, Changbo, Chen, Chang, Shan, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579414/
https://www.ncbi.nlm.nih.gov/pubmed/33132912
http://dx.doi.org/10.3389/fphar.2020.577062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579414/
https://www.ncbi.nlm.nih.gov/pubmed/33132912
http://dx.doi.org/10.3389/fphar.2020.577062

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