Doxorubicin cardiomyopathy is ameliorated by acacetin via Sirt1‐mediated activation of AMPK/Nrf2 signal molecules

Doxorubicin cardiotoxicity is frequently reported in patients undergoing chemotherapy. The present study investigates whether cardiomyopathy induced by doxorubicin can be improved by the natural flavone acacetin in a mouse model and uncovers the potential molecular mechanism using cultured rat cardi...

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Detalles Bibliográficos
Autores principales: Wu, Wei‐Yin, Cui, Yu‐Kai, Hong, Yi‐Xiang, Li, Yun‐Da, Wu, Yao, Li, Gang, Li, Gui‐Rong, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579684/
https://www.ncbi.nlm.nih.gov/pubmed/32918384
http://dx.doi.org/10.1111/jcmm.15859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579684/
https://www.ncbi.nlm.nih.gov/pubmed/32918384
http://dx.doi.org/10.1111/jcmm.15859

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