The AKR1C3/AR‐V7 complex maintains CRPC tumour growth by repressing B4GALT1 expression

Multiple mechanisms contribute to the survival and growth of metastatic castration‐resistant prostate cancer (mCRPC) cells without androgen, including androgen receptor splice variants (AR‐V) and de novo intratumoral androgen synthesis. AKR1C3 is a critical androgenic enzyme that plays different rol...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Wu, Shiqi, Fang, Yong, Sun, Guangxi, He, Dalin, Hsieh, Jer‐Tsong, Wang, Xinyang, Zeng, Hao, Wu, Kaijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579719/
https://www.ncbi.nlm.nih.gov/pubmed/32902124
http://dx.doi.org/10.1111/jcmm.15831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579719/
https://www.ncbi.nlm.nih.gov/pubmed/32902124
http://dx.doi.org/10.1111/jcmm.15831

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