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SIRT1 promotes pulmonary artery endothelial cell proliferation by targeting the Akt signaling pathway

Pulmonary arterial hypertension (PAH) is a disease characterized by a progressive increase in pulmonary vascular resistance and obliterative pulmonary vascular remodeling; however, the pathogenesis of the disease is not completely understood. Sirtuin 1 (SIRT1) is a histone deacetylase involved in ce...

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Detalles Bibliográficos
Autores principales: Xi, Liandong, Ruan, Lin, Yao, Xiaoguang, Zhang, Dong, Yuan, Hongwei, Li, Qiang, Yan, Cuihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579766/
https://www.ncbi.nlm.nih.gov/pubmed/33101469
http://dx.doi.org/10.3892/etm.2020.9309