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Cell type-specific genotoxicity in estrogen-exposed ovarian and fallopian epithelium
BACKGROUND: Loss of the genomic stability jeopardize genome stability and promote malignancies. A fraction of ovarian cancer (OvCa) arises from pathological mutations of DNA repair genes that result in highly mutagenic genomes. However, it remains elusive why the ovarian epithelial cells are particu...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579787/ https://www.ncbi.nlm.nih.gov/pubmed/33087072 http://dx.doi.org/10.1186/s12885-020-07524-7 |