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Cell type-specific genotoxicity in estrogen-exposed ovarian and fallopian epithelium

BACKGROUND: Loss of the genomic stability jeopardize genome stability and promote malignancies. A fraction of ovarian cancer (OvCa) arises from pathological mutations of DNA repair genes that result in highly mutagenic genomes. However, it remains elusive why the ovarian epithelial cells are particu...

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Detalles Bibliográficos
Autores principales:	Song, Liang, Tang, Zizhi, Peng, Changsheng, Yang, Yueming, Guo, Chang, Wang, Danqing, Guo, Liandi, Chen, Jie, Liu, Cong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579787/ https://www.ncbi.nlm.nih.gov/pubmed/33087072 http://dx.doi.org/10.1186/s12885-020-07524-7

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