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microRNA-451a promoter methylation regulated by DNMT3B expedites bladder cancer development via the EPHA2/PI3K/AKT axis

BACKGROUND: The downregulation of microRNA (miR)-451a has been reported in bladder cancer (BCa) tissues. Herein, we elucidated the role of miR-451a in BCa with the involvement of DNA methyltransferase 3B (DNMT3B). METHODS: We first screened the differentially expressed miRNAs from the serum of 12 BC...

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Detalles Bibliográficos
Autores principales:	Liu, Beibei, Sun, Wei, Gao, Wuyue, Li, Liqiang, Cao, Zhenxue, Yang, Xiaohuai, Liu, Jianmin, Guo, Yuanyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579823/ https://www.ncbi.nlm.nih.gov/pubmed/33087088 http://dx.doi.org/10.1186/s12885-020-07523-8

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