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Aging-relevant human basal forebrain cholinergic neurons as a cell model for Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is an adult-onset mental disorder with aging as a major risk factor. Early and progressive degeneration of basal forebrain cholinergic neurons (BFCNs) contributes substantially to cognitive impairments of AD. An aging-relevant cell model of BFCNs will critically...

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Detalles Bibliográficos
Autores principales: Ma, Shuaipeng, Zang, Tong, Liu, Meng-Lu, Zhang, Chun-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579825/
https://www.ncbi.nlm.nih.gov/pubmed/33087140
http://dx.doi.org/10.1186/s13024-020-00411-6