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Aging-relevant human basal forebrain cholinergic neurons as a cell model for Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) is an adult-onset mental disorder with aging as a major risk factor. Early and progressive degeneration of basal forebrain cholinergic neurons (BFCNs) contributes substantially to cognitive impairments of AD. An aging-relevant cell model of BFCNs will critically...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579825/ https://www.ncbi.nlm.nih.gov/pubmed/33087140 http://dx.doi.org/10.1186/s13024-020-00411-6 |