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Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro
BACKGROUND: Cerebral malaria (CM) is associated with morbidity and mortality despite the use of potent anti-malarial agents. Brain endothelial cell activation and dysfunction from oxidative and inflammatory host responses and products released by Plasmodium falciparum-infected erythrocytes (IE), are...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579885/ https://www.ncbi.nlm.nih.gov/pubmed/33087130 http://dx.doi.org/10.1186/s12936-020-03447-7 |