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Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro

BACKGROUND: Cerebral malaria (CM) is associated with morbidity and mortality despite the use of potent anti-malarial agents. Brain endothelial cell activation and dysfunction from oxidative and inflammatory host responses and products released by Plasmodium falciparum-infected erythrocytes (IE), are...

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Detalles Bibliográficos
Autores principales: Mita-Mendoza, Neida K., Magallon-Tejada, Ariel, Parmar, Priyanka, Furtado, Raquel, Aldrich, Margaret, Saidi, Alex, Taylor, Terrie, Smith, Joe, Seydel, Karl, Daily, Johanna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579885/
https://www.ncbi.nlm.nih.gov/pubmed/33087130
http://dx.doi.org/10.1186/s12936-020-03447-7