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Considerations for feature selection using gene pairs and applications in large-scale dataset integration, novel oncogene discovery, and interpretable cancer screening

BACKGROUND: Advancements in transcriptomic profiling have led to the emergence of new challenges regarding data integration and interpretability. Variability between measurement platforms makes it difficult to compare between cohorts, and large numbers of gene features have encouraged the use black...

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Detalles Bibliográficos
Autores principales: Moody, Laura, Chen, Hong, Pan, Yuan-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579924/
https://www.ncbi.nlm.nih.gov/pubmed/33087122
http://dx.doi.org/10.1186/s12920-020-00778-x