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Complementary NAD(+) replacement strategies fail to functionally protect dystrophin-deficient muscle

BACKGROUND: Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disorder stemming from a loss of functional dystrophin. Current therapeutic options for DMD are limited, as small molecule modalities remain largely unable to decrease the incidence or mitigate the consequences of repetiti...

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Detalles Bibliográficos
Autores principales: Frederick, David W., McDougal, Alan V., Semenas, Melisa, Vappiani, Johanna, Nuzzo, Andrea, Ulrich, John C., Becherer, J. David, Preugschat, Frank, Stewart, Eugene L., Sévin, Daniel C., Kramer, H. Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579925/
https://www.ncbi.nlm.nih.gov/pubmed/33092650
http://dx.doi.org/10.1186/s13395-020-00249-y