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Complementary NAD(+) replacement strategies fail to functionally protect dystrophin-deficient muscle
BACKGROUND: Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disorder stemming from a loss of functional dystrophin. Current therapeutic options for DMD are limited, as small molecule modalities remain largely unable to decrease the incidence or mitigate the consequences of repetiti...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579925/ https://www.ncbi.nlm.nih.gov/pubmed/33092650 http://dx.doi.org/10.1186/s13395-020-00249-y |