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Improving lung cancer risk stratification leveraging whole transcriptome RNA sequencing and machine learning across multiple cohorts

BACKGROUND: Bronchoscopy for suspected lung cancer has low diagnostic sensitivity, rendering many inconclusive results. The Bronchial Genomic Classifier (BGC) was developed to help with patient management by identifying those with low risk of lung cancer when bronchoscopy is inconclusive. The BGC wa...

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Detalles Bibliográficos
Autores principales: Choi, Yoonha, Qu, Jianghan, Wu, Shuyang, Hao, Yangyang, Zhang, Jiarui, Ning, Jianchang, Yang, Xinwu, Lofaro, Lori, Pankratz, Daniel G., Babiarz, Joshua, Walsh, P. Sean, Billatos, Ehab, Lenburg, Marc E., Kennedy, Giulia C., McAuliffe, Jon, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579926/
https://www.ncbi.nlm.nih.gov/pubmed/33087128
http://dx.doi.org/10.1186/s12920-020-00782-1