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CXCL1 contributes to IL-6 expression in osteoarthritis and rheumatoid arthritis synovial fibroblasts by CXCR2, c-Raf, MAPK, and AP-1 pathway

BACKGROUND: Osteoarthritis (OA) and rheumatoid arthritis (RA) are common joint disorders that are considered to be different diseases due to their unique molecular mechanisms and pathogenesis. Chemokines and their corresponding receptors have been well characterized in RA progression, but less so in...

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Detalles Bibliográficos
Autores principales: Hou, Sheng-Mou, Chen, Po-Chun, Lin, Chieh-Mo, Fang, Mei-Ling, Chi, Miao-Ching, Liu, Ju-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580030/
https://www.ncbi.nlm.nih.gov/pubmed/33087182
http://dx.doi.org/10.1186/s13075-020-02331-8