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Generation of Regionally Specified Human Brain Organoids Resembling Thalamus Development

Thalamus is a critical information relay hub in the cortex; its malfunction causes multiple neurological and psychiatric disorders. However, there are no model systems to study the development and function of human thalamus. Here, we present a protocol to generate regionally specified human brain or...

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Detalles Bibliográficos
Autores principales: Xiang, Yangfei, Cakir, Bilal, Park, In-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580078/
https://www.ncbi.nlm.nih.gov/pubmed/33103124
http://dx.doi.org/10.1016/j.xpro.2019.100001