Protocol to Generate Senescent Cells from the Mouse Hepatic Cell Line AML12 to Study Hepatic Aging

Previously developed senescent primary fibroblast models have limited relevance to study age-related changes in metabolically active tissues such as the liver. Here, we describe a protocol to generate senescent cells from the mouse hepatic cell line, AML12. These senescent cells exhibit molecular an...

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Detalles Bibliográficos
Autores principales: Tripathi, Madhulika, Yen, Paul Michael, Singh, Brijesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580094/
https://www.ncbi.nlm.nih.gov/pubmed/33111102
http://dx.doi.org/10.1016/j.xpro.2020.100064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580094/
https://www.ncbi.nlm.nih.gov/pubmed/33111102
http://dx.doi.org/10.1016/j.xpro.2020.100064

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