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Generating Patient-Derived Gliomas within Cerebral Organoids

Glioblastoma (GBM) remains a devastating disease with a median survival of less than two years. Current preclinical models are unable to accurately reflect the complexity of human GBM. We recently established a cerebral organoid glioma (GLICO) model to study the invasion and biology of patient-deriv...

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Detalles Bibliográficos
Autores principales: Linkous, Amanda, Fine, Howard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580125/
https://www.ncbi.nlm.nih.gov/pubmed/33103125
http://dx.doi.org/10.1016/j.xpro.2019.100008