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Generating Patient-Derived Gliomas within Cerebral Organoids
Glioblastoma (GBM) remains a devastating disease with a median survival of less than two years. Current preclinical models are unable to accurately reflect the complexity of human GBM. We recently established a cerebral organoid glioma (GLICO) model to study the invasion and biology of patient-deriv...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580125/ https://www.ncbi.nlm.nih.gov/pubmed/33103125 http://dx.doi.org/10.1016/j.xpro.2019.100008 |