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Rosmarinic Acid Prevents Radiation-Induced Pulmonary Fibrosis Through Attenuation of ROS/MYPT1/TGFβ1 Signaling Via miR-19b-3p

The mechanism of pulmonary fibrosis caused by irradiation remains obscure. Since rosmarinic acid (RA) have anti-oxidant and anti-inflammatory properties, we aimed to evaluate the effect of RA on the X-ray-induced lung injury. Male rats received RA (30, 60, or 120 mg/kg) 7 days before 15 Gy of X-ray...

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Detalles Bibliográficos
Autores principales: Zhang, Tingting, Ma, Shanshan, Liu, Chang, Hu, Kai, Xu, Meng, Wang, Rensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580151/
https://www.ncbi.nlm.nih.gov/pubmed/33149731
http://dx.doi.org/10.1177/1559325820968413