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Using Chromatin Accessibility to Delineate Therapeutic Subtypes in Pancreatic Cancer Patient-Derived Cell Lines

Disrupted chromatin regulatory processes contribute to the development of cancer, in particular pancreatic ductal adenocarcinoma. The assay for transposase accessible chromatin with high-throughput sequencing (ATAC-seq) is typically used to study chromatin organization. Here, we present a revised AT...

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Detalles Bibliográficos
Autores principales: Brunton, Holly, Garner, Ian M., Bailey, Ulla-Maja, Upstill-Goddard, Rosie, Bailey, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580199/
https://www.ncbi.nlm.nih.gov/pubmed/33111113
http://dx.doi.org/10.1016/j.xpro.2020.100079