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Using Chromatin Accessibility to Delineate Therapeutic Subtypes in Pancreatic Cancer Patient-Derived Cell Lines
Disrupted chromatin regulatory processes contribute to the development of cancer, in particular pancreatic ductal adenocarcinoma. The assay for transposase accessible chromatin with high-throughput sequencing (ATAC-seq) is typically used to study chromatin organization. Here, we present a revised AT...
Autores principales: | Brunton, Holly, Garner, Ian M., Bailey, Ulla-Maja, Upstill-Goddard, Rosie, Bailey, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580199/ https://www.ncbi.nlm.nih.gov/pubmed/33111113 http://dx.doi.org/10.1016/j.xpro.2020.100079 |
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