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Establishment and Use of Patient-Derived Xenograft Models for Drug Testing in Head and Neck Squamous Cell Carcinoma

This protocol provides the steps required for the establishment of patient-derived xenograft (PDX) tumors for head and neck squamous cell carcinomas (HNSCCs) and their utility in examining drug responses. PDXs recapitulate the heterogeneity observed in the corresponding human tumors, which makes the...

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Detalles Bibliográficos
Autores principales: Karamboulas, Christina, Meens, Jalna, Ailles, Laurie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580210/
https://www.ncbi.nlm.nih.gov/pubmed/33111077
http://dx.doi.org/10.1016/j.xpro.2020.100024