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Repurposing the Native Type I-F CRISPR-Cas System in Pseudomonas aeruginosa for Genome Editing

Repurposing the broadly distributed native CRISPR-Cas systems in prokaryotes for genome editing is emerging as a new strategy for genetic manipulations. We recently reported the establishment of a single plasmid-mediated, one-step genome-editing technique in a multidrug-resistant genotype of the opp...

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Detalles Bibliográficos
Autores principales: Xu, Zeling, Li, Yanran, Yan, Aixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580218/
https://www.ncbi.nlm.nih.gov/pubmed/33111087
http://dx.doi.org/10.1016/j.xpro.2020.100039