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Imaging of Telomerase RNA by Single-Molecule Inexpensive FISH Combined with Immunofluorescence
Fluorescent in situ hybridization (FISH) on the RNA moiety of human telomerase (hTR) with 50-mer probes detects hTR RNA accumulated in Cajal bodies. Using both live-cell imaging and single-molecule inexpensive FISH, our published work revealed that only a fraction of hTR localizes to Cajal bodies, w...
Autores principales: | Querido, Emmanuelle, Sfeir, Agnel, Chartrand, Pascal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580239/ https://www.ncbi.nlm.nih.gov/pubmed/33111129 http://dx.doi.org/10.1016/j.xpro.2020.100104 |
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