Transcriptome Analyses of β-Thalassemia −28(A>G) Mutation Using Isogenic Cell Models Generated by CRISPR/Cas9 and Asymmetric Single-Stranded Oligodeoxynucleotides (assODNs)

β-thalassemia, caused by mutations in the human hemoglobin β (HBB) gene, is one of the most common genetic diseases in the world. The HBB −28(A>G) mutation is one of the five most common mutations in Chinese patients with β-thalassemia. However, few studies have been conducted to understand how t...

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Detalles Bibliográficos
Autores principales: Li, Jing, Zhou, Ziheng, Sun, Hai-Xi, Ouyang, Wenjie, Dong, Guoyi, Liu, Tianbin, Ge, Lei, Zhang, Xiuqing, Liu, Chao, Gu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580707/
https://www.ncbi.nlm.nih.gov/pubmed/33193694
http://dx.doi.org/10.3389/fgene.2020.577053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580707/
https://www.ncbi.nlm.nih.gov/pubmed/33193694
http://dx.doi.org/10.3389/fgene.2020.577053

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