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Self-amplifying RNA vaccines for infectious diseases

Vaccinology is shifting toward synthetic RNA platforms which allow for rapid, scalable, and cell-free manufacturing of prophylactic and therapeutic vaccines. The simple development pipeline is based on in vitro transcription of antigen-encoding sequences or immunotherapies as synthetic RNA transcrip...

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Detalles Bibliográficos
Autores principales: Bloom, Kristie, van den Berg, Fiona, Arbuthnot, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580817/
https://www.ncbi.nlm.nih.gov/pubmed/33093657
http://dx.doi.org/10.1038/s41434-020-00204-y