Cargando…

Self-amplifying RNA vaccines for infectious diseases

Vaccinology is shifting toward synthetic RNA platforms which allow for rapid, scalable, and cell-free manufacturing of prophylactic and therapeutic vaccines. The simple development pipeline is based on in vitro transcription of antigen-encoding sequences or immunotherapies as synthetic RNA transcrip...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bloom, Kristie, van den Berg, Fiona, Arbuthnot, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580817/ https://www.ncbi.nlm.nih.gov/pubmed/33093657 http://dx.doi.org/10.1038/s41434-020-00204-y

Ejemplares similares

Production, Characterization, and Assessment of Permanently Cationic and Ionizable Lipid Nanoparticles for Use in the Delivery of Self-Amplifying RNA Vaccines
por: Kairuz, Dylan, et al.
Publicado: (2023)

Advancing mRNA technologies for therapies and vaccines: An African context
por: Kairuz, Dylan, et al.
Publicado: (2022)

Self-Amplifying RNA Viruses as RNA Vaccines
por: Lundstrom, Kenneth
Publicado: (2020)

Silencing hepatitis B virus covalently closed circular DNA: The potential of an epigenetic therapy approach
por: Singh, Prashika, et al.
Publicado: (2021)

Gene Therapy for Chronic HBV—Can We Eliminate cccDNA?
por: Bloom, Kristie, et al.
Publicado: (2018)

Recent Update on the Role of Circular RNAs in Hepatocellular Carcinoma
por: Ely, Abdullah, et al.
Publicado: (2021)

An Update on Self-Amplifying mRNA Vaccine Development
por: Blakney, Anna K., et al.
Publicado: (2021)

Design of Effective Primary MicroRNA Mimics With Different Basal Stem Conformations
por: van den Berg, Fiona T, et al.
Publicado: (2016)

Self-Amplifying RNA Vaccine Candidates: Alternative Platforms for mRNA Vaccine Development
por: Schmidt, Christin, et al.
Publicado: (2023)

Inactivation of Hepatitis B Virus Replication in Cultured Cells and In Vivo with Engineered Transcription Activator-Like Effector Nucleases
por: Bloom, Kristie, et al.
Publicado: (2013)

Development of nucleic acid vaccines: use of self-amplifying RNA in lipid nanoparticles
por: Rodríguez-Gascón, Alicia, et al.
Publicado: (2014)

Self-Amplifying Replicon RNA Vaccine Delivery to Dendritic Cells by Synthetic Nanoparticles
por: McCullough, Kenneth C., et al.
Publicado: (2014)

Diversity of Dysregulated Long Non-Coding RNAs in HBV-Related Hepatocellular Carcinoma
por: Samudh, Nazia, et al.
Publicado: (2022)

Reinventing the nucleic acid vaccine with self-amplifying RNA
por: Geall, AJ, et al.
Publicado: (2012)

Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines
por: Blakney, Anna K., et al.
Publicado: (2021)

Advances with RNAi-Based Therapy for Hepatitis B Virus Infection
por: van den Berg, Fiona, et al.
Publicado: (2020)

Self-Replicating RNA Viruses for Vaccine Development against Infectious Diseases and Cancer
por: Lundstrom, Kenneth
Publicado: (2021)

Inhibition of replication of hepatitis B virus using transcriptional repressors that target the viral DNA
por: Bloom, Kristie, et al.
Publicado: (2019)

Healthcare Settings as Amplifiers of Infectious Disease
por: Chiarello, Linda A., et al.
Publicado: (2004)

Formulation, inflammation, and RNA sensing impact the immunogenicity of self-amplifying RNA vaccines
por: Tregoning, John S., et al.
Publicado: (2022)

Self-Amplifying RNA Approach for Protein Replacement Therapy
por: Papukashvili, Dimitri, et al.
Publicado: (2022)

A new generation of vaccines based on alphavirus self-amplifying RNA
por: Ballesteros-Briones, María Cristina, et al.
Publicado: (2020)

Hepatitis B Virus Research in South Africa
por: Maepa, Mohube B., et al.
Publicado: (2022)

Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines
por: Anderluzzi, Giulia, et al.
Publicado: (2020)

Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ
por: Cu, Yen, et al.
Publicado: (2013)

Delivery of self-amplifying RNA vaccines in in vitro reconstituted virus-like particles
por: Biddlecome, Adam, et al.
Publicado: (2019)

Progress in the use of RNA interference as a therapy for chronic hepatitis B virus infection
por: Weinberg, Marc S, et al.
Publicado: (2010)

Improved Specificity and Safety of Anti-Hepatitis B Virus TALENs Using Obligate Heterodimeric FokI Nuclease Domains
por: Smith, Tiffany, et al.
Publicado: (2021)

Enhanced immune responses following heterologous vaccination with self-amplifying RNA and mRNA COVID-19 vaccines
por: Elliott, Tamara, et al.
Publicado: (2022)

The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency
por: Anderluzzi, Giulia, et al.
Publicado: (2022)

Development of a potent Zika virus vaccine using self-amplifying messenger RNA
por: Luisi, Kate, et al.
Publicado: (2020)

Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses
por: Vogel, Annette B., et al.
Publicado: (2018)

A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability
por: Voigt, Emily A., et al.
Publicado: (2022)

Adenoviral Vectors: Potential as Anti-HBV Vaccines and Therapeutics
por: Farhad, Tasneem, et al.
Publicado: (2022)

The Development of mRNA Vaccines for Infectious Diseases: Recent Updates
por: Nitika,, et al.
Publicado: (2021)

Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice
por: Spencer, Alexandra J., et al.
Publicado: (2021)

Climate Change and Cascading Risks from Infectious Disease
por: Semenza, Jan C., et al.
Publicado: (2022)

Self-disseminating vaccines for emerging infectious diseases
por: Murphy, Aisling A., et al.
Publicado: (2016)

Suboptimal Herd Performance Amplifies the Spread of Infectious Disease in the Cattle Industry
por: Gates, M. Carolyn, et al.
Publicado: (2014)

Evaluation of a self-amplifying mRNA reporter vaccine in explant models of broiler chickens
por: Snoeck, Janne, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_a2dv3jnm673p39k2olqf0diviu